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Gestational trophoblastic disease

Definition

Gestational trophoblastic disease (GTD) is a group of conditions in which tumors grow inside a woman's uterus (womb). The abnormal cells start in the tissue that would normally become the placenta, the organ that develops during pregnancy to feed the fetus.

A baby may or may not develop during these types of pregnancies.

There are several types of GTD.

References

Goldstein DP, Berkowitz RS. Gestational trophoblastic disease. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. . 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 94.

McGee J, Covens A. Gestational trophoblastic disease: hydatidiform mole, nonmetastatic and metastatic gestational trophoblastic tumor: diagnosis and management. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL. . 6th ed. Philadelphia, Pa: Mosby Elsevier; 2012:chap 35.

Braunstein GD. Endocrine changes in pregnancy. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. . 12th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 21.

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