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Leukemia

Definition

Leukemia is a type of blood cancer that begins in the bone marrow. Bone marrow is the soft tissue in the center of the bones, where blood cells are produced.

The term leukemia means white blood. White blood cells (leukocytes) are used by the body to fight infections and other foreign substances. Leukocytes are made in the bone marrow.

Leukemia leads to an uncontrolled increase in the number of white blood cells.

The cancerous cells prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made. Life-threatening symptoms can then develop.

The cancer cells can spread to the bloodstream and lymph nodes. They can also travel to the brain and spinal cord (the central nervous system) and other parts of the body.

Leukemias are divided into two major types:

  • Acute (which progresses quickly)
  • Chronic (which progresses more slowly)

The different types of leukemia are:

Causes, incidence, and risk factors

Symptoms

Signs and tests

Treatment

Support Groups

Expectations (prognosis)

Complications

Calling your health care provider

Prevention

References

Appelbaum FR. The acute leukemias. In: Goldman L, Schafer AI, eds. . 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 189.

Kantarjian H, O'brien S. The chronic leukemias. In: Goldman L, Schafer AI, eds. . 24th ed. Philadelphia, PA: Elsevier Saunders; 2011:chap 190.

Encyclopedia content is provided as information only and not intended to replace the advice and instruction from your personal physician.