Waterhouse-Friderichsen syndrome is failure of the adrenal gland due to bleeding into the gland.
Causes, incidence, and risk factors
This condition is caused by severe infection with meningococcus bacteria or other severe infection from bacteria, such as:
Rarely, Waterhouse-Friderichsen syndrome can be caused by the use of medications that promote blood clotting. Other causes include:
Signs and tests
It is deadly if not treated right away.
Calling your health care provider
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Maitra A. The endocrine system. In: Kumar V, Abbas AK, Fausto N, Aster JC, eds. . 8th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 24.
White PC. Adrenocortical insufficiency. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. . 19th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 569.