Malabsorption is difficulty absorbing nutrients from food.
Causes, incidence, and risk factors
Many diseases can cause malabsorption. Malabsorption is usually the inability to absorb certain sugars, fats, proteins, or vitamins from food. It can also involve a general malabsorption of food.
Some of the causes of malabsorption include:
- and HIVAIDS
- Biliary atresia
- Celiac disease
- Certain medications (cholestyramine, tetracycline, some antacids, some medications used to treat obesity, colchicine, acarbose, phenytoin)
- Certain types of cancer (lymphoma, pancreatic cancer , gastrinomas)
- Certain types of surgery (gastrectomy with gastrojejunostomy, surgical treatments for obesity , partial or complete removal of the ileum)
- Chronic liver disease
- Cow's milk protein intolerance
- Crohn's disease
- Damage from radiation treatments
- Parasite infection, including
- Soy milk protein intolerance
- Whipple's disease
Vitamin B12 malabsorption may be due to:
- Bloating, cramping, and gas
- Bulky stools
- Chronic diarrhea (may not occur with vitamin malabsorption)
- Failure to thrive
- Fatty stools (steatorrhea)
- Muscle wasting
- Weight loss
Malabsorption can affect growth and development, or it can lead to specific illnesses.
Signs and tests
Vitamin and nutrient replacement is often necessary.
The outlook depends on the condition causing malabsorption.
Long-term malabsorption can result in:
Calling your health care provider
Call your health care provider if you notice symptoms of malabsorption.
Preventive methods depend on the condition causing malabsorption.
Semrad CE. Approach to the patient with diarrhea and malabsorption. In Goldman L, Schafer AI, eds. . 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 142.
Hogenauer C, Hammer HF. Maldigestion and malabsorption. In: Feldman M, Friedman LS, Brandt LJ eds.. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 101.