Simple pulmonary eosinophilia
Simple pulmonary eosinophilia is swelling (inflammation) of the lungs from an increase in eosinophils, a type of white blood cell.
Pulmonary infiltrates with eosinophilia; Loeffler syndrome
Causes, incidence, and risk factors
Most cases of simple pulmonary eosinophilia are due to an allergic reaction from:
- A drug, such as a sulfonamide antibiotic or nonsteroidal anti-inflammatory drug (NSAID)
- Infection with a fungus such as or
- A parasite, including the roundworms hookworms , , or ()
The symptoms can range from none at all to severe. They may go away without treatment.
Signs and tests
The health care provider will listen to your chest with a stethoscope. Crackle-like sounds called rales may be heard. Rales suggest inflammation of the lung tissue.
A complete blood count (CBC) may show increased white blood cells, particularly eosinophils .
usually shows abnormal shadows called infiltrates. They may disappear with time or reappear in different areas of the lung.Chest x-ray
A bronchoscopy with washing may show a large number of eosinophils.
Gastric lavage may show signs of the Ascaris worm or another parasite.
If you are allergic to a drug, the doctor may tell you to stop taking it. (Never stop taking a medication without first talking with your doctor.)
If the condition is due to an infection, you may be treated with an antibiotic or anti-parasitic medication.
Sometimes, you may need corticosteroids (powerful anti-inflammatory medicines).
The disease often goes away without treatment. If treatment is needed, the response is usually good. However, relapses can occur (the disease comes back).
A rare complication of simple pulmonary eosinophilia is a severe type of pneumonia called acute idiopathic eosinophilic pneumonia.
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